Cold Spring Harbor Laboratory FY2021 filing

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The organization conducts research in the biological sciences with a particular emphasis on basic research in molecular biology and genetics.

501(c)(3) charity; gifts are tax-deductible.
85¢ of each $1 spent went to programs.
$4.7M paid to officers and key staff.
Mission: Form 990 Part I, line 1 · Status: IRS Pub. 78 · Programs: Part IX · Pay: Part VII

Before you give

FY2021 · Form 990Independent: from IRS data, not the org
Download 990
IRS status
501(c)(3)
not on the IRS revocation list
Looks good: listed by the IRS and not on the revocation list.
IRS BMF · Auto-Revocation List
Tax-deductible gifts
Yes
Donations are tax-deductible
Looks good: the IRS lists gifts to it as deductible.
IRS Pub. 78 · IRS BMF
Latest return
FY2024
latest Form 990
Looks good: the latest return is for FY2024, 2 tax years back; within 2 tax years.
IRS e-file · Filing history
Surplus or deficit
5 of 5
filings with a surplus
Average surplus $34.8M a year · 16% of revenue · last 5 filings
Looks good: a surplus in 5 of the last 5 filings.
Pt I · Ln 19 · 5 filings
Spent on programs
85%
of spending
Looks good: 85% of spending went to programs; 75% or more.
Pt IX · Ln 25 · col B
Pay to officers and key staff
$4.7M
to officers and key staff · 3% of spending
Looks good: pay to officers and key staff is 3% of spending; 15% or less.
Pt VII · Sec A
8 mo
of spending, in cash
Plus $646.1M in investments, Pt X · Ln 11–13
Looks good: 7.6 months of spending in cash; 3 or more.
Pt X · Ln 1–2 · Pt I · Ln 18
Named funders
2
named funders · $270K
Fine: 2 funders name it on their filings; under 3.
Funders’ Sch. I, 990-PF
Liabilities
$184.6M
16% of total assets
Looks good: liabilities are 16% of assets; 50% or less.
Pt X · Ln 26
Independent board members
31
of 32 voting members
Looks good: 31 of 32 voting members are independent, a majority.
Pt VI · Ln 1a–1b
Looks goodFineWorth a lookConcernNo data yetTap a box for the reason.
Revenue
$202.3M
+10% vs prior year
Spent
$170.4M
To programs
85%
Net assets
$990.6M
By yearFY2020–FY2024
Revenue
$202.3M
FY2021▲ +10%
Tap a bar for its year
Revenue by fiscal year
FY2020$184.4M
FY2021$202.3M
FY2022$207.4M
FY2023$258.0M
FY2024$232.7M
Expenses
$170.4M
FY2021▲ +3%
Tap a bar for its year
Expenses by fiscal year
FY2020$166.0M
FY2021$170.4M
FY2022$184.0M
FY2023$190.7M
FY2024$199.8M
Net assets
$990.6M
FY2021▲ +10%
Tap a bar for its year
Net assets by fiscal year
FY2020$899.0M
FY2021$990.6M
FY2022$961.2M
FY2023$1.1B
FY2024$1.1B

From the FY2021 Form 990 · figures checked against the IRS filing · see the original

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You’re viewing the FY2021 filing — not the latest on file. See the latest (FY2024) →

Is it real?

Yes. Never revoked by the IRS. Latest filing on record: FY2024. IRS ruling in Aug 1964.

IRS Pub. 78 · IRS Auto-Revocation List · IRS Business Master File

Where the money goes

85 cents of each dollar spent went to programs.

Program services 85% · $145.0M Management & general 14% · $23.7M Fundraising 1% · $1.7M

Form 990 Part IX, line 25, columns B–D. Every line is in By the numbers.

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Who runs it and what they're paid

43 people listed on the 990; $4.7M paid to officers and key staff.

Part VII, Section A · reportable compensation
CEO and Trustee
$775,721Pt VII · Sec A
Chief Operating Officer
$533,702Pt VII · Sec A
Director of Research
$455,437Pt VII · Sec A
Scientist
$403,943Pt VII · Sec A
$399,761Pt VII · Sec A
VP, Sponsored Programs
$379,082Pt VII · Sec A
Scientist
$374,763Pt VII · Sec A
VP Advancement
$373,502Pt VII · Sec A

Bruce Stillman PHD’s $975K as CEO and Trustee is at the 60th percentile of top reported officer pay among 43 $100M+ science & technology nonprofits. Peer set: organizations in the same NTEE major field of work and revenue-size band, compared on each org’s own highest-paid officer/key-employee, from Form 990 Part VII / 990-PF Part VIII. Descriptive placement, not a verdict on whether the pay is appropriate.

Compensation history total reportable pay by year · 8 named individuals · Part VII

NameFY2024FY2023FY2022FY2021FY2020
Bruce Stillman PHD$975,312$3,033,951$855,081$775,721$774,869
David Spector—$907,784$479,909$455,437$456,290
John Tuke$584,160$568,098$549,125$533,702$547,035
David Tuveson$543,180$436,086$425,578$403,943$400,335
Michael Wigler$440,079$427,233$417,452$399,761$400,645
Charles V Prizzi$427,202$418,828$407,116$373,502$364,427
Nicholas Milowski$413,390$76,560———
Anthony Zador$410,471$397,761$382,252$374,763—

Total reportable compensation (Form 990 Part VII column D / Schedule J column E) by filing year, matched by name within this organization. The Schedule J base / bonus / deferred breakdown is not parsed into this dataset.

See Cold Spring Harbor Laboratory executive salaries →

Questions the 990 asks

The form asks each of these directly. These are the filed answers.

  • Family or business ties among officersPt VI · Ln 2No
  • Top official's pay set by an independent reviewPt VI · Ln 15aYes
  • Loans to or from officersSch L · Pt II1 listed

Programs and updates

Conducts basic research in molecular biology and genetics while publishing scientific journals and books to advance and spread global knowledge of the biological sciences.

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3 programs · $140.0M · in their own filed words · FY2021
01

Research

Cold spring harbor laboratory (CSHL), founded in 1890, is a world-renowned, private research and education institution with research programs in cancer, neuroscience, plant biology, quantitative biology, and bioinformatics & genomics.

$118.9Mprogram expense
02

Educational Meetings & Courses Program

CSHL'S reputation as one of the premier hubs of activity in biology and genetics is linked to its meetings and courses program. With roots in the legendary annual symposia in quantitative biology series, which began in 1933, the program organizes more than 60 meetings and courses annually, covering a wide range of topics in the…

$11.6Mprogram expense
03

Publications

With origins in the 1930's, CSHL press enhances the laboratory's educational mission by publishing original work that assists in the advance and spread of scientific knowledge. Sale of its publications enhances the laboratory's international reputation for excellence.

$9.5Mprogram expense

Funders

Who pays for it.

From grant filings on record. Receipts are incomplete: individual donors are never listed.

Grants

Schedule I · received and paid
Grants received · FY2025
Total grants receivedfrom 2 funders$270K
Grants paid · 131 grants · $44.9M · 2020–2023
New York Genome Center INCNY · FY2023$592,395
Regents Univ of CaliforniaCA · FY2023$500,426
NYU School of MedicineNY · FY2023$433,652
Northwell HealthNY · FY2023$431,794
The Broad Institute INCMA · FY2023$428,839
Duke UniversityNC · FY2023$424,120
Johns Hopkins UniversityMD · FY2023$352,010
University of MassachusettsFY2023$238,000
Allen InstituteWA · FY2023$233,414
Jackson LaboratoryME · FY2023$205,468
State University of New York- BinghamtonFY2023$194,316
New York UniversityNY · FY2023$105,850
See all 131 grants →

Federal money

Single Audit · Federal Audit Clearinghouse · money spent from federal programs
Year ending Dec 2025 · $53.3M federal money spent
Cancer Biology ResearchDepartment of Health and Human Services · ALN 93.396 · Direct and through Cornell University and 1 more$9.2M
Biomedical Research and Research TrainingDepartment of Health and Human Services · ALN 93.859 · Direct$6.8M
Extramural Research Programs in the Neurosciences and Neurological DisordersDepartment of Health and Human Services · ALN 93.853 · Direct and through New York University and 5 more$6.3M
Mental Health Research GrantsDepartment of Health and Human Services · ALN 93.242 · Direct and through Thomas Jefferson University and 4 more$5.4M
Cancer Centers Support GrantsDepartment of Health and Human Services · ALN 93.397 · Direct$4.7M

Plus 19 smaller programs.

The auditor reported no findings.

Year ending Dec 2024 · $57.2M federal money spent
Cancer Biology ResearchDepartment of Health and Human Services · ALN 93.396 · Direct and through Cornell University$8.6M
Mental Health Research GrantsDepartment of Health and Human Services · ALN 93.242 · Direct and through Duke University and 6 more$7.7M
Extramural Research Programs in the Neurosciences and Neurological DisordersDepartment of Health and Human Services · ALN 93.853 · Direct and through New York University and 5 more$7.1M
Biomedical Research and Research TrainingDepartment of Health and Human Services · ALN 93.859 · Direct$7.0M
Biological SciencesNational Science Foundation · ALN 47.074 · Direct and through New York University and 1 more$5.2M

Plus 21 smaller programs.

The auditor reported no findings.

Year ending Dec 2023 · $57.9M federal money spent
Mental Health Research GrantsDepartment of Health and Human Services · ALN 93.242 · Direct and through Duke University and 4 more$13.0M
Cancer Biology ResearchDepartment of Health and Human Services · ALN 93.396 · Direct and through Weill Medical College of Cornell University$8.9M
Extramural Research Programs in the Neurosciences and Neurological DisordersDepartment of Health and Human Services · ALN 93.853 · Direct and through Oregon Health & Science and 6 more$6.0M
Biomedical Research and Research TrainingDepartment of Health and Human Services · ALN 93.859 · Direct$5.8M
Biological SciencesNational Science Foundation · ALN 47.074 · Direct and through New York University and 1 more$4.5M

Plus 24 smaller programs.

The auditor reported no findings.

Year ending Dec 2022 · $62.1M federal money spent
Mental Health Research GrantsDepartment of Health and Human Services · ALN 93.242 · Direct and through Univ Calif S.d. and 4 more$18.9M
Cancer Biology ResearchDepartment of Health and Human Services · ALN 93.396 · Direct$10.2M
Extramural Research Programs in the Neurosciences and Neurological DisordersDepartment of Health and Human Services · ALN 93.853 · Direct and through Oregon Health & Sci and 6 more$6.3M
Biomedical Research and Research TrainingDepartment of Health and Human Services · ALN 93.859 · Direct$5.1M
Cancer Centers Support GrantsDepartment of Health and Human Services · ALN 93.397 · Direct$4.5M

Plus 23 smaller programs.

The auditor reported no findings.

By the numbers

The FY2021 990, line by line.

1The main four
Money inPt VIII
$202.3M
Ln 12
Gifts and grantsLn 1h$146.3M
Investment incomeLn 3$26.1M
Other incomeLn 4–11$15.4M
Money outPt IX
$170.4M
Ln 25
Programscol B$145.0M
Managementcol C$23.7M
Fundraisingcol D$1.7M
Owns and owesPt X
$990.6M
net assets · Ln 32
Cash and savingsLn 1–2$107.7M
Total assetsLn 16$1.2B
LiabilitiesLn 26$184.6M
PeoplePt VI, VII
43
listed · VII A
PaidVII A11
Voting boardVI 1a32
IndependentVI 1b31
2In more detail
Revenue in detailPt VIII
Gifts and grantsLn 1h$146.3M
Government grantsLn 1e$59.1M
Noncash giftsLn 1g$911K
Fundraising eventsLn 1c$5.5M
Fees for servicesLn 2g$14.5M
Investment incomeLn 3$26.1M
Other incomeLn 4–11$15.4M
Gains on assetsLn 7$24.4M
Total revenueLn 12$202.3M
Assets in detailPt X, end of year
CashLn 1$8K
SavingsLn 2$107.7M
Cash and savings togetherLn 1–2$107.7M
Pledges and grants receivableLn 3$120.2M
Accounts receivableLn 4$2.5M
Loans to officers and key peopleLn 5$273K
Inventories for sale or useLn 8$212K
Prepaid expenses and deferred chargesLn 9$2.3M
Land, buildings, equipmentLn 10c$284.9M
InvestmentsLn 11–13$646.1M
Other assetsLn 15$10.9M
Total assetsLn 16$1.2B
LiabilitiesLn 26$184.6M
Net assetsLn 32$990.6M
OperationsPt I, VI
EmployeesI 51,195
VolunteersI 647
Fiscal year endsHeaderDecember
Conflict-of-interest policyVI 12aYes
Whistleblower policyVI 13Yes
Records policyVI 14Yes
3More from this return
BondsSch K, Pt X
Tax-exempt bond debt owedX 20$96.0M
Bond issues listedSch K Pt I1
Raised by those issuesSch K Pt I$55.0M
Abroad and in kindSch F, M
Grants to other countriesSch F Pt II–III$806K
Noncash gifts receivedSch M Pt I$911K
Investment feesPt IX, Sch D
Investment fees, as reportedPt IX 11f$2.7M
Share of the $646.4M endowmentSch D 1g0.41%
Typical, median of 1,806 orgs0.44%
EndowmentSch D · Pt V
LineFY21FY20FY19FY18FY17
End of yearLn 1g$646.4M$589.2M$545.2M$427.6M$411.3M
Given inLn 1b$8.8M$5.7M$66.1M$53.6M$11.6M
SpentLn 1d–1f$25.7M$23.3M$22.7M$19.0M$16.4M
4Year over year
Balance sheet, start vs end of yearPt X · col A, B
LineStart FY21End FY21
Cash and savingsLn 1–2$107.0M$107.7M
InvestmentsLn 11–13$598.8M$646.1M
Land, buildings, equipmentLn 10c$266.3M$284.9M
Total assetsLn 16$1.11B$1.18B
LiabilitiesLn 26$210.1M$184.6M
Net assetsLn 32$899.0M$990.6M
5Every line
Statement of functional expensesPt IX · every line
LineTotalProgramsManagementFundraising
Grants to domestic organizationsLn 1$13.0M$13.0M
Grants and assistance to foreign recipientsLn 3$806K$806K
Pay of current officers, directors and key staffLn 5$3.5M$1.8M$1.6M$107K
Other salaries and wagesLn 7$63.9M$53.6M$9.3M$1.1M
Pension plan contributionsLn 8$4.8M$4.0M$717K$88K
Other employee benefitsLn 9$9.3M$8.0M$1.2M$113K
Payroll taxesLn 10$4.3M$3.5M$687K$63K
Management feesLn 11a$2.2M$1.4M$792K$2K
Legal feesLn 11b$440K$223K$217K
Accounting feesLn 11c$351K$351K
Lobbying feesLn 11d$48K$48K
Professional fundraising feesLn 11e$2K$2K
Investment management feesLn 11f$2.7M$2.7M
Advertising and promotionLn 12$428K$417K$10K
Office expensesLn 13$22.4M$21.5M$890K$36K
Information technologyLn 14$2.4M$2.1M$285K
RoyaltiesLn 15$721K$721K
OccupancyLn 16$7.0M$6.3M$691K
TravelLn 17$173K$161K$10K$1K
Conferences, conventions and meetingsLn 19$1.6M$1.6M$5K$100
InterestLn 20$4.1M$3.3M$736K
Depreciation, depletion and amortizationLn 22$16.1M$14.1M$1.9M
InsuranceLn 23$1.2M$29K$1.1M
Other expenses (24a–d)Ln 24$9.1M$8.4M$515K$191K
Total functional expensesLn 25$170.4M$145.0M$23.7M$1.7M

Filing history

YearMoney inMoney outIn minus outNet assetsDownload
FY2024 LatestFiled with the IRS Nov 12, 2025 $232.7M$199.8M$32.9M$1.1B 990 PDF
FY2023Filed with the IRS Nov 5, 2024 $258.0M$190.7M$67.3M$1.1B 990 PDF
FY2022Filed with the IRS Nov 6, 2023 $207.4M$184.0M$23.4M$961.2M 990 PDF
FY2021 ViewingFiled with the IRS Dec 1, 2022 $202.3M$170.4M$31.8M$990.6M 990 PDF
FY2020Filed with the IRS Nov 12, 2021 $184.4M$166.0M$18.5M$899.0M 990 PDF

Schedules filed Part IV

III · Programs R · Related orgs G · Fundraising L · Interested persons I · Grants A · Public support F · Foreign M · Noncash J · Pay O · Explanations
See the full FY2021 990 (6 parts)
Part I · Summary $202,293,920 revenue, 12 lines filed
I-8 Contributions and grantsPrior year $126,503,073$146,346,976
I-9 Program service revenuePrior year $14,892,876$14,464,860
I-10 Investment incomePrior year $27,641,456$26,102,790
I-11 Other revenuePrior year $15,397,303$15,379,294
I-12 Total revenuePrior year $184,434,708$202,293,920
I-13 Grants and similar amounts paidPrior year $13,177,001$13,828,729
I-14 Benefits paid to membersPrior year $0$0
I-15 Salaries and benefitsPrior year $85,432,622$85,843,716
I-16a Professional fundraising feesPrior year $39,875$2,000
I-17 Other expensesPrior year $67,315,152$70,772,832
I-18 Total expensesPrior year $165,964,650$170,447,277
I-19 Revenue less expensesPrior year $18,470,058$31,846,643
Part VI · Governance 31 of 32 board members independent, no flags
VI-1a Voting members of the governing body32
VI-1b Independent voting members31
VI-2 Family or business relationship among officers or directorsNo
VI-12a Written conflict of interest policyYes
VI-13 Written whistleblower policyYes
VI-14 Document retention and destruction policyYes
VI-15a Process for setting top official's payYes
Part VIII · Statement of revenue $202,293,920 across 14 lines filed
VIII-1c Fundraising events$5,547,143
VIII-1d Related organizations$5,441,312
VIII-1e Government grants$59,100,574
VIII-1f All other contributions, gifts and grants$76,257,947
VIII-1g Noncash contributions (included above)$910,590
VIII-1h Total contributions, gifts and grants$146,346,976
VIII-2a-f Program service revenue, itemized rows (sum of 2a–2f as filed)Related to mission $14,226,483 · Unrelated business $238,377$14,464,860
VIII-3 Investment incomeUnrelated business −$317,219 · Excluded from tax $2,039,921$1,722,702
VIII-5 RoyaltiesExcluded from tax $14,066,754$14,066,754
VIII-6 Net rental income or lossExcluded from tax $1,021,243$1,021,243
VIII-7 Net gain or loss on sales of assetsExcluded from tax $24,380,088$24,380,088
VIII-8 Net income from fundraising eventsExcluded from tax −$49,551−$49,551
VIII-11a-d Other revenue, itemized rows (sum of 11a–11d as filed)Excluded from tax $340,848$340,848
VIII-12 Total revenueRelated to mission $14,226,483 · Unrelated business −$78,842 · Excluded from tax $41,799,303$202,293,920
Part IX · Statement of functional expenses $170,447,277 across 24 lines filed
IX-1 Grants to domestic organizationsPrograms $13,022,510$13,022,510
IX-3 Grants and assistance to foreign recipientsPrograms $806,219$806,219
IX-5 Pay of current officers, directors and key staffPrograms $1,778,113 · Management $1,604,909 · Fundraising $106,821$3,489,843
IX-7 Other salaries and wagesPrograms $53,591,421 · Management $9,261,178 · Fundraising $1,090,715$63,943,314
IX-8 Pension plan contributionsPrograms $4,003,666 · Management $717,340 · Fundraising $88,495$4,809,501
IX-9 Other employee benefitsPrograms $7,998,109 · Management $1,236,164 · Fundraising $113,290$9,347,563
IX-10 Payroll taxesPrograms $3,503,942 · Management $686,923 · Fundraising $62,630$4,253,495
IX-11a Management feesPrograms $1,362,290 · Management $791,846 · Fundraising $1,741$2,155,877
IX-11b Legal feesPrograms $222,629 · Management $217,239$439,868
IX-11c Accounting feesManagement $350,994$350,994
IX-11d Lobbying feesFundraising $48,000$48,000
IX-11e Professional fundraising feesFundraising $2,000$2,000
IX-11f Investment management feesManagement $2,654,511$2,654,511
IX-12 Advertising and promotionPrograms $417,412 · Management $10,469$427,881
IX-13 Office expensesPrograms $21,480,263 · Management $889,911 · Fundraising $36,272$22,406,446
IX-14 Information technologyPrograms $2,119,827 · Management $284,734$2,404,561
IX-15 RoyaltiesPrograms $720,807$720,807
IX-16 OccupancyPrograms $6,326,784 · Management $690,718$7,017,502
IX-17 TravelPrograms $161,420 · Management $9,861 · Fundraising $1,348$172,629
IX-19 Conferences, conventions and meetingsPrograms $1,588,352 · Management $4,592 · Fundraising $100$1,593,044
IX-20 InterestPrograms $3,321,543 · Management $735,549$4,057,092
IX-22 Depreciation, depletion and amortizationPrograms $14,135,877 · Management $1,927,579$16,063,456
IX-23 InsurancePrograms $28,964 · Management $1,145,494$1,174,458
IX-24 Other expenses (24a–d)Programs $8,380,180 · Management $514,812 · Fundraising $190,714$9,085,706
IX-25 Total functional expensesPrograms $144,970,328 · Management $23,734,823 · Fundraising $1,742,126$170,447,277
Part X · Balance sheet $1,175,223,746 assets, 23 lines filed
X-1 Cash, non-interest-bearingStart of year $8,110$8,111
X-2 Savings and temporary cash investmentsStart of year $106,970,232$107,707,062
X-3 Pledges and grants receivableStart of year $121,017,697$120,247,405
X-4 Accounts receivableStart of year $2,283,845$2,527,049
X-5 Loans to officers and key peopleStart of year $326,640$272,625
X-6 Loans to other insidersStart of year $0$0
X-7 Notes and loans receivableStart of year $0$0
X-8 Inventories for sale or useStart of year $239,573$212,306
X-9 Prepaid expenses and deferred chargesStart of year $1,792,229$2,294,951
X-10c Land, buildings and equipment, netStart of year $266,250,473$284,939,853
X-11 Publicly traded securitiesStart of year $153,874,676$147,707,960
X-12 Other securitiesStart of year $444,938,049$498,375,760
X-15 Other assetsStart of year $11,429,254$10,930,664
X-16 Total assetsStart of year $1,109,130,778$1,175,223,746
X-17 Accounts payable and accrued expensesStart of year $17,292,201$10,827,985
X-19 Deferred revenueStart of year $54,826,194$43,125,253
X-20 Tax-exempt bond liabilitiesStart of year $95,940,233$96,006,502
X-25 Other liabilitiesStart of year $42,068,231$34,682,583
X-26 Total liabilitiesStart of year $210,126,859$184,642,323
X-27 Net assets without donor restrictionsStart of year $595,785,997$691,930,703
X-28 Net assets with donor restrictionsStart of year $303,217,922$298,650,720
X-32 Total net assets or fund balancesStart of year $899,003,919$990,581,423
X-33 Total liabilities and net assetsStart of year $1,109,130,778$1,175,223,746
Part XI · Reconciliation of net assets $990,581,423 net assets at year end
XI-1 Total revenue$202,293,920
XI-2 Total expenses$170,447,277
XI-3 Revenue less expenses$31,846,643
XI-4 Net assets at start of year$899,003,919
XI-5 Net unrealized gains (losses) on investments$52,449,092
XI-9 Other changes in net assets$7,281,769
XI-10 Net assets at end of year$990,581,423

Form 990 e-file (XML) FY2021 from the IRS · Classification, formation year and address from the IRS Business Master File

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