Is it real?
Yes. Never revoked by the IRS. Latest filing on record: FY2025. IRS ruling in Apr 2024.
IRS Pub. 78 · IRS Auto-Revocation List · IRS Business Master File
Where the money goes
77 cents of each dollar spent went to programs.
Form 990 Part IX, line 25, columns B–D. Every line is in By the numbers.
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Who runs it and what they're paid
6 people listed on the 990; $220K paid to officers and key staff.
Joe Torres Beg 3-2025’s $75K as President is at the 9th percentile of top reported officer pay among 360 $1–10M medical research nonprofits. Peer set: organizations in the same NTEE major field of work and revenue-size band, compared on each org’s own highest-paid officer/key-employee, from Form 990 Part VII / 990-PF Part VIII. Descriptive placement, not a verdict on whether the pay is appropriate.
Compensation history total reportable pay by year · 4 named individuals · Part VII
| Name | FY2025 | FY2024 |
|---|---|---|
| Joe Torres Beg 3-2025 | $75,000 | — |
| Brian Wang VP Thru 3-2025 | $74,776 | — |
| Alexander Kleinman Beg 3-2025 | $69,802 | — |
| Brian Wang | — | $31,178 |
Total reportable compensation (Form 990 Part VII column D / Schedule J column E) by filing year, matched by name within this organization. The Schedule J base / bonus / deferred breakdown is not parsed into this dataset.
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Questions the 990 asks
The form asks each of these directly. These are the filed answers.
- Family or business ties among officersPt VI · Ln 2No
- Top official's pay set by an independent reviewPt VI · Ln 15aYes
Programs and updates
Advance science and innovation to develop medical countermeasures against pandemic threats.
Questions for Active Site Research INC
Your first name shows with your question. Active Site Research INC answers here, for everyone.
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The Synthetic Innate Immunity program aims to develop medicines that serve as society's first line of defense against emerging viral outbreaks by taking inspiration from natural mechanisms of innate immunity.
PAN-2025-001 is a single-site, two-arm, parallel-group superiority randomized controlled trial (RCT) with 1:1 allocation, designed to evaluate whether large language model (LLM) use improves the ability of novice lab participants to independently perform complex biological tasks.
The organization periodically provides subject-matter expertise in molecular biology and related life sciences disciplines to AI companies. Such services include responding to technical inquiries and developing advanced scientific problem sets designed to evaluate complex biological reasoning and analytical capabilities in emerging AI…
Funders
Who pays for it.
From grant filings on record. Receipts are incomplete: individual donors are never listed.
Grants
By the numbers
The FY2025 990, line by line.
Download 990
| Line | Start FY25 | End FY25 |
|---|---|---|
| Cash and savingsLn 1–2 | $90K | $1.0M |
| InvestmentsLn 11–13 | $0 | |
| Land, buildings, equipmentLn 10c | $0 | |
| Total assetsLn 16 | $127K | $1.4M |
| LiabilitiesLn 26 | $18K | $37K |
| Net assetsLn 32 | $109K | $1.3M |
| Line | Total | Programs | Management | Fundraising |
|---|---|---|---|---|
| Grants to domestic organizationsLn 1 | $0 | |||
| Grants to domestic individualsLn 2 | $0 | |||
| Grants and assistance to foreign recipientsLn 3 | $0 | |||
| Benefits paid to or for membersLn 4 | $0 | |||
| Pay of current officers, directors and key staffLn 5 | $226K | $182K | $32K | $12K |
| Pay of disqualified personsLn 6 | $0 | |||
| Other salaries and wagesLn 7 | $52K | $42K | $7K | $3K |
| Pension plan contributionsLn 8 | $0 | |||
| Other employee benefitsLn 9 | $1K | $870 | $239 | $81 |
| Payroll taxesLn 10 | $22K | $18K | $3K | $1K |
| Management feesLn 11a | $0 | |||
| Legal feesLn 11b | $14K | $111 | $14K | |
| Accounting feesLn 11c | $25K | $25K | ||
| Lobbying feesLn 11d | $0 | |||
| Professional fundraising feesLn 11e | $0 | |||
| Investment management feesLn 11f | $0 | |||
| Other fees for servicesLn 11g | $43K | $35K | $7K | $500 |
| Advertising and promotionLn 12 | $16K | $3K | $13K | $52 |
| Office expensesLn 13 | $21K | $15K | $6K | |
| Information technologyLn 14 | $13K | $5K | $8K | |
| RoyaltiesLn 15 | $0 | |||
| OccupancyLn 16 | $159K | $62K | $95K | $2K |
| TravelLn 17 | $7K | $2K | $2K | $3K |
| Travel and entertainment for public officialsLn 18 | $0 | |||
| Conferences, conventions and meetingsLn 19 | $0 | |||
| InterestLn 20 | $0 | |||
| Payments to affiliatesLn 21 | $0 | |||
| Depreciation, depletion and amortizationLn 22 | $0 | |||
| InsuranceLn 23 | $4K | $4K | ||
| Other expenses (24a–d)Ln 24 | $449K | $444K | $4K | |
| All other expensesLn 24e | $2K | $733 | $939 | |
| Total functional expensesLn 25 | $1.1M | $811K | $222K | $21K |
Filing history
| Year | Money in | Money out | In minus out | Net assets | Download |
|---|---|---|---|---|---|
| FY2025 Latest Viewing | $2.3M | $1.1M | $1.2M | $1.3M | 990 PDF |
| FY2024 | $854K | $745K | $109K | $109K | 990 PDF |
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Schedules filed Part IV
See the full FY2025 990 (6 parts)
Part I · Summary $2,258,848 revenue, 12 lines filed
Part VI · Governance 3 of 4 board members independent, 1 to look at
Part VIII · Statement of revenue $2,258,848 across 10 lines filed
Part IX · Statement of functional expenses $1,053,220 across 31 lines filed
Part X · Balance sheet $1,352,366 assets, 19 lines filed
Part XI · Reconciliation of net assets $1,314,904 net assets at year end
Form 990 e-file (XML) FY2025 from the IRS · Classification, formation year and address from the IRS Business Master File
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