Senior Program Manager, Scientist

Key Responsibilities

Portfolio & Program Management Lead and coordinate a portfolio of concurrent research programs spanning multiple principal investigators, timelines, and funding mechanisms. Develop, implement, and maintain program management tools including project plans, milestone trackers, risk registers, and dashboards. Facilitate cross-functional team meetings, track action items, and ensure accountability across scientific and administrative stakeholders. Identify and resolve operational bottlenecks and interdependencies that may affect program timelines or scientific deliverables.

Support strategic planning efforts, including program prioritization, resource allocation, and go/no-go decision frameworks. NIH Grant Administration & Reporting Serve as the program-level point of contact for large NIH grants (e.g., R01, P01, U01, U54, RM1), coordinating all administrative and scientific reporting requirements. Prepare, compile, and submit annual Progress Reports (RPPRs), non-competing renewals, supplements, and other required NIH correspondence. Monitor grant budgets, expenditure timelines, and ensure compliance with NIH terms and conditions in coordination with sponsored research offices.

Track deliverables, milestones, and publication requirements across multi-project and multi-site awards. Coordinate with NIH Program Officers and other agency contacts as needed to address administrative or scientific programmatic matters. Grant Writing & Scientific Communication Write, edit, and contribute to all sections of grant applications including Specific Aims, Research Strategy, human subjects/vertebrate animal sections, biosketches , and resource/environment pages. Prepare white papers, concept papers, letters of intent, and responses to RFAs/PAs across NIH and other federal or private funding agencies.

Draft scientific summaries, program highlights, and lay-language communications for institutional and external audiences. Support manuscript preparation, including literature reviews, methods sections, and figure/table organization for peer-reviewed publications. Scientific Contribution – Mouse Genetics & Therapeutic Development Provide scientific input and oversight on programs involving mouse genetics, including transgenic, knock-in, knock-out, and conditional models. Contribute expertise in preclinical therapeutic development pipelines, including target identification, in vivo efficacy studies, and translational modeling.

Critically evaluate experimental designs, interpret results, and ensure scientific rigor across program deliverables. Engage with scientific collaborators and external partners (academic, industry, and government) to advance program goals. Stay current with literature and emerging methodologies relevant to mouse genetics, neuroscience, rare disease, or other applicable therapeutic areas. Compliance, Regulatory & Operational Oversight Ensure all animal research activities are conducted in compliance with IACUC protocols…

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