Why St Jude Children's Research Hospital
FY2024 · Form 990Its mission and biggest programs, as filedTreats and researches catastrophic childhood diseases globally while training medical professionals, ensuring no child is denied care regardless of their family's ability to pay.
- Research: the current basic science and clinical Research at the Hospital includes work in gene therapy, chemotherapy, the biochemistry of normal and cancerous cells, radiation treatment, blood diseases, resistance to therapy, viruses, neurological diseases, hereditary diseases, influenza, pediatric aids and…$883.2M spent in FY2024
- Patient care: the Hospital provided 17,927 inpatient days of care during the year. Our bone marrow transplantation program accounted for 3,805 or 21% of those inpatient days. Patients made 74,651 clinic registrations during the year.$726.7M spent in FY2024
- Education and training: as part of its mission, the institution has developed a global initiative (St. Jude global) to improve the survival rates of children with cancer and other catastrophic diseases worldwide. St. Jude global accomplishes this by sharing knowledge…$146.2M spent in FY2024
Before you apply
FY2023 · Form 990Independent: from IRS data, not the orgAbout the role
The org's own posting, as writtenJoin our Team! The Abraham Laboratory in the Department of Computational Biology at St. Jude Children's Research Hospital is seeking an innovative and collaborative Scientist to investigate how gene regulation and nuclear organization shape mammalian cell identity and contribute to disease, including pediatric cancers. This is an exciting bench-based role for a hands-on experimental scientist who is passionate about uncovering the mechanisms that control gene expression.
The successful candidate will study cis- and trans- regulatory mechanisms using cutting-edge molecular biology technologies and independently design and execute high-throughput functional genomics assays Working at the intersection of molecular biology, functional genomics, and cancer biology, you will design and execute cutting-edge experiments that advance our understanding of how regulatory elements such as enhancers and super-enhancers drive normal development and disease.
As a key member of a highly collaborative multidisciplinary team, you will lead and contribute to research projects utilizing advanced genomic technologies, cell-based systems, and imaging approaches to answer fundamental biological questions with direct relevance to human health. Ideal Candidate The ideal candidate is a highly independent, hands-on scientist with strong troubleshooting skills and a collaborative mindset. This individual will serve as a key experimental partner within a shared-resource environment, working across multiple research projects focused on gene regulation and functional genomics. Candidates are not required to have expertise in every area listed.
We welcome individuals with experience in a combination of these techniques who are eager to expand their skill set and contribute across diverse research projects.
Experience in some combination of the following areas is preferred: Molecular & Cellular Biology Molecular cloning Cell culture and tissue culture Viral transduction and cell line engineering Tissue processing and sample handling Functional Genomics & Omics Technologies Strong hands-on experience with at least one high-throughput sequencing-based assay such as: ChIP-seq CUT&RUN ATAC-seq RNA-seq Hi-C or related genomic technologies Ability to independently troubleshoot and optimize genomics workflows Imaging & Cellular Phenotyping Immunofluorescence staining DNA and RNA FISH Confocal microscopy Cellular imaging-based assays Preferred / Nice-to-Have Experience Massively Parallel Reporter Assays (MPRA) High-throughput functional genomic screening Research involving transcriptional condensates, enhancer biology, or gene regulatory mechanisms Experience generating and analyzing large-scale genomic datasets Projects This Scientist May Support Depending on their expertise and project needs, the successful candidate may contribute to initiatives involving: MPRA-based functional genomics studies DNA and RNA imaging assays Transcriptional condensate biology Enhancer and super-enhancer…
About St Jude Children's Research Hospital
From its Form 990- Budget $2.21B · Health Care
- Staff 7,862 · founded 1959
- Pays its leaders $793K–$1.6M (12 reported)
- Open jobs 200 · Jobs at St Jude Children's Research Hospital · Full 990 report