Job · Palo Alto, CA

Scientist/Sr. Scientist, Spatial Omics Technology Development (Fixed-Term Contract)

Arc Research Institute · Medical Research · $122.3M budget · 3 staff · Since 2021

Why Arc Research Institute

FY2024 · Form 990Its mission and biggest programs, as filed

Accelerate scientific progress and understand complex diseases to improve human health.

  • - Core Investigators (which include the following labs) are provided with no-strings-attached, multi-year funding as well as cutting-edge scientific and infrastructure support to enable high-risk, high-reward science. They are innovative pioneers enabled to pursue their very best ideas. The Gilbert…$64.1M spent in FY2024

Before you apply

FY2024 · Form 990Independent: from IRS data, not the org
Pays its leaders
$246K–$1.1M
12 officers reported
Fine: from the org's Form 990.
Pt VII · Sec A
Budget
$82.8M
spent in FY2024
Fine: from the org's Form 990.
Pt I · Ln 18
Staff
3
employees
3 volunteers
Fine: from the org's Form 990.
Pt I · Ln 5–6
Spent on programs
77%
of spending
Looks good: 77% of spending went to programs; 75% or more.
Pt IX · Ln 25 · col B
Surplus or deficit
+32%
of revenue, FY2024
Looks good: revenue was at least expenses in the latest filing.
Pt I · Ln 19
Cash reserves
15 mo
of spending, in cash and securities
Looks good: 14.6 months of spending in cash; 3 or more.
Pt X · Ln 1–2 · Pt I · Ln 18
Latest return
FY2024
latest Form 990
Looks good: the latest return is for FY2024, 2 tax years back; within 2 tax years.
IRS e-file
IRS status
501(c)(3)
tax-exempt since 2022
Looks good: listed by the IRS.
IRS BMF
Looks goodFineWorth a lookConcernTap a box for the reason.

About the role

The org's own posting, as written

About Arc Institute Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases. Founded in 2021 and based in Palo Alto, Arc partners with Stanford University, UC Berkeley, and UC San Francisco. Unlike academia, our scientists have long-term funding and industry-like resources. Unlike industry, they're free to pursue high-risk, long-term research without commercial pressures.

Arc's Technology Centers and Core Investigator labs work side by side, integrating experimental and computational biology under one roof to tackle problems neither could solve alone. Our two Institute Initiatives reflect this model in action: Virtual Cell Initiative : Building a full-stack virtual cell model to identify disease mechanisms and nominate drug targets, accelerating the path from biological insight to clinical trials. Alzheimer's Disease Initiative : Mapping the genes, pathways, and environmental factors behind Alzheimer's disease to develop drug candidates that address root causes.

More than 300 Arconauts work together at our Palo Alto headquarters, backed by substantial long-term philanthropic funding. About the position We are looking for an outstanding scientist / senior scientist for a fixed term of 18 months to join our Multi-Omic Technology Center focusing on imaging-based spatial technology development for the Alzheimer's Disease Initiative.

You will work closely with the spatial technology lead and collaborators across Arc tech centers and innovation investigators, to stabilize a custom imaging platform, adapt homebrew chemistry to arrayed human organoids, and help move our in-house spatial perturb-seq technology from proof-of-concept to a screen-ready platform for large scale studies. The ideal candidate has a passion for developing technologies and robust systems and has a track record in spatial publications or product development. The role will split between system characterization/improvement and spatial multiomic (mRNA + protein + sgRNA) chemistry/workflow optimization/ execution.

This is an excellent opportunity for a highly motivated scientist interested in the intersection of academic research and biotech system/product development. This 18-month fixed-term position is based onsite 5 days a week in Palo Alto. This role is not eligible for visa sponsorship. About you Curious, adaptable learner: You track state-of-the-art spatial technologies, exercise sound judgment adopting new methods, and pivot readily as priorities shift. Natural troubleshooter: You enjoy diagnosing hardware, chemistry, and software issues on an early-stage custom platform, staying calm and methodical under pressure.

High-quality finisher: You find creative solutions and follow through with reproducible, high-quality results. Systems thinker and process optimizer: You design for scale, building reliable technology for…

Read the full posting

About Arc Research Institute

From its Form 990

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